Saturday, February 24, 2018

Fat Build-up - Fat Reduction - Lipogenesis - Lipolysis - Research and Science



Important literature review paper

Mechanisms of nutritional and hormonal regulation of lipogenesis
Sander Kerstena
EMBO Rep. 2001 Apr 15; 2(4): 282–286.


Fasting and Lipolysis – Part 4
Essentially, fasting is the gradual shift of burning glucose to burning fat.
Jason Fung
https://idmprogram.com/fasting-and-lipolysis-part-4/

Essentially, fasting is the gradual shift of burning glucose to burning fat.
Studies of eating a single meal per day found significantly more fat loss despite the same caloric intake. Importantly, no evidence of muscle loss was found.
 Alternate daily fasting over 22 days found no measurable decrease in Total Energy Expenditure. There was no ‘starvation’ mode. There was no decreased metabolism. Fat oxidation increased 58% while carbohydrate oxidation decreased from 53%.   This means that the body has started to switch over from burning sugar to burning fat with no overall drop in energy. Four days of fasting actually increase TEE by 12%.
Fasting Myths – Part 5
Jason Fung
https://idmprogram.com/fasting-myths-part-5/




2017
Preventing weight regain
Attenuating the Biologic Drive for Weight Regain Following Weight Loss: Must What Goes Down Always Go Back Up?
Christopher L. Melby, Hunter L. Paris, Rebecca M. Foright  and James Peth
Nutrients 2017, 9(5), 468;
http://www.mdpi.com/2072-6643/9/5/468/htm


2014

High insulin levels tied to obesity pathway
August 25, 2014
UT Southwestern Medical Center
A link between high levels of insulin and pathways that lead to obesity has been discovered by researchers. The finding  may have important implication in the treatment of protocol of diabetes. The discovery was made by studying mice engineered to lack receptors for a hormone called glucagon. Insulin was given to them to control Type II diabetes.
https://www.sciencedaily.com/releases/2014/08/140825185319.htm


2009
Muscle acylcarnitines during short-term fasting in lean healthy men.
Maarten R Soeters, Hans P. Sauerwein, Marinus Duran, Ronald J. Wanders, Mariëtte T Ackermans,
et al.. Muscle acylcarnitines during short-term fasting in lean healthy men. Clinical Science, Portland
Press, 2009, 116 (7), pp.585-592.
https://hal.archives-ouvertes.fr/hal-00479449/document

2000

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine.
Zauner C1, Schneeweiss B, Kranz A, Madl C, Ratheiser K, Kramer L, Roth E, Schneider B, Lenz K.
Am J Clin Nutr. 2000 Jun;71(6):1511-5.
https://www.ncbi.nlm.nih.gov/pubmed/10837292




Effect of starvation and very low calorie diets on protein-energy interrelationships in lean and obese subjects
M. ELIA*

* Dunn Clinical Nutrition Centre, 100 Tennis Court Road, Cambridge, CB2 1QL, U.K.
http://archive.unu.edu/unupress/food2/UID07E/UID07E11.HTM

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