Tuesday, April 26, 2022

Weight Gain in Summer

 

In the summer, body weight can go up by several pounds due to increased body water. This is accomplished through fluid-conserving hormones such as aldosterone, which allows the kidney to retain more fluid and reduces the amount of salt in sweat, a measure that also aids in water retention. The increase and stabilization of total body water can only be accomplished by continuing to exercise in hot weather and will not occur in people who spend most of their time indoors in air-conditioned environments.


https://www.scientificamerican.com/article/experts-body-wieght-ambient-temperature/


https://timesofindia.indiatimes.com/life-style/health-fitness/weight-loss/weight-loss-ways-water-could-be-making-you-gain-weight/photostory/78020546.cms


https://www.fatherly.com/health-science/why-am-i-gaining-weight-summer-fat/

12 Tissue Remedies - ENT Diseases

 

https://archive.org/stream/twelvetissuerem00boer/twelvetissuerem00boer_djvu.txt

https://californiahomeopath.com/about-the-journal/




CALCAREA FLUOR1CA. 

Synonyms. — Calcii Fluoridum. Calcium Fluoride. Cal- carea Fluorata. 

Common Name. — Fluorspar. Fluoride of Lime. 

Page 37

Ears. — Calcareous deposits on the tympani. Mastoid disease when periosteum is affected. 

Nose. — Cold in the head, ineffectual desire to sneeze, stuffy cold, dry coryza, ozsena. Copious, offensive, thick, greenish, lumpy, yellow nasal discharge. Osseous growths. Affections of nasal bones ; odor of dead bone disappears after use of the remedy. Adenoid growths in post-nasal space and pharynx. 

Face. — Hard swelling on the cheek with pain or toothache, hard swelling on the jawbone, cold sores rather small, hard herpetic sores on lips from cold, not diffused like Natr. mur. 

Mouth. — Gumboil with hard swelling on the jaw, stony hard swelling on the jawbone. Cold sores at corner of mouth. Great dryness of mouth. 

Tongue. — Cracked appearance of the tongue with or with- out pain. Induration of the tongue, hardening after inflammation. 

Teeth. — Enamel of the teeth rough and deficient. Unnatural looseness of the teeth with or without pain, teeth become loose in their sockets. Malnutrition of the teeth. Toothache with pain if any food touches the tooth. Tooth- ache with a looseness of the teeth. 

Throat. — Diphtheria when the affection has gone to the windpipe. Relaxed throat with tickling in the larynx when caused by elongation of the uvula. Uvula relaxed, causing irritation, tickling and cough. Hawking of mucus in the morning. Burning in throat better by warm drinks. Great dryness of throat 

Sunday, April 24, 2022

About Vitamin B12

 Cobalamin is the only water-soluble vitamin stored in the body. About 3 mg of cobalamin are stored, of which 1 mg is stored in the liver. Hence, it takes 3-5 years to develop a vitamin B12 deficiency after a total gastrectomy. In contrast, significant amounts of folate are not stored. Clinical evidence of folate deficiency can occur within a month after folate intake is stopped.

https://www.medscape.com/answers/204066-119195/what-is-the-role-of-cobalamin-and-folate-storage-in-the-pathogenesis-of-megaloblastic-anemia


https://www.b12-vitamin.com/body-store/


However, this impression is put into perspective if you consider the actual intake: from the 1000 µg, only a maximum of 12 µg is actually absorbed by the body with a single oral dose; only 480% of the daily requirement (2). 

https://www.b12-vitamin.com/high-dose/



One review recommended that those with vitamin B12 deficiency take 1 mg of vitamin B12 daily for a month, followed by a maintenance dose of 125–250 mcg per day (18Trusted Source).

https://www.healthline.com/nutrition/vitamin-b12-dosage#suggested-dosages

Typically, about 56 percent of a 1-microgram dose of B-12 is absorbed, and that rate of absorption decreases drastically if you take more than 2 micrograms at a time, the Office of Dietary Supplements explains. For example, if you take a 500-microgram pill, your body absorbs only about 10 micrograms.


 But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.

https://www.webmd.com/a-to-z-guides/vitamin-b12-test

HealthVit Vitamin B12 500mcg Tablet
West-Coast Pharmaceutical Works Ltd
https://www.1mg.com/otc/healthvit-vitamin-b12-500mcg-tablet-otc340915

Wednesday, April 20, 2022

Hypothyroid and Homeopathy

 


Thyroid Problems and Diseases


https://www.askdrshah.com/app/underactive-thyroid/thyroid-medicines.aspx


https://jish-mldtrust.com/love-me-only-at-all-times-the-case-of-a-young-woman-with-hypothyroidism/


https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6b4c9dc2-bf57-48a4-9f61-7e4a54f4eadd

Tuesday, April 5, 2022

Vajikarana: Treatment of Sexual Dysfunctions in Ayurveda

 

Very interesting introductory article

Vajikarana: Treatment of sexual dysfunctions based on Indian concepts

P. K. Dalal, Adarsh Tripathi, and S. K. Gupta 

Indian J Psychiatry. 2013 Jan; 55(Suppl 2): S273–S276.  doi: 10.4103/0019-5545.105550

PMCID: PMC3705695PMID: 23858267

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705695/



https://charaka.org/vajikarana/



Vajikarana Adhyaya

Chikitsa Sthana Chapter 2. Aphrodisiac therapy, virility and treatment of sexual dysfunctions

https://www.carakasamhitaonline.com/index.php/Vajikarana_Adhyaya


Vajikarana : Sexology in Ayurveda


Prof. Dr. Pandurang Kulkarni, Dr. Swapnil Daspute, Prof. Dr. Abhinandan Muke, Prof. Dr. Atul Rakshe, Dr. Ruturaj Kadam Patil

Deerghayu International, 04-Oct-2020 - Social Science - 194 pages


' Sex is one of basic desire in animal kingdom. Every body should take care of own body , mind and soul. Food is very important. Ayurveda has used it as Rasayana/ rejuvenator of body and mind. Food and plants are used as aphrodisiacs meaning Vajikaran. This is very important branch of Ayurveda. Various sexual problems related to Males are described with remedies.

https://books.google.co.in/books/about/Vajikarana_Sexology_in_Ayurveda.html?id=6BQBEAAAQBAJ

Monday, April 4, 2022

Corona Disease 19 - Covid 19 - Treatment - Research Papers and News Summaries



Long Covid

Gastrointestinal sequelae 90 days after discharge for COVID-19
The Lancet, VOLUME 6, ISSUE 5, P344-346, MAY 01, 2021
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(21)00076-5/fulltext

COVID-19 infection causing residual gastrointestinal 
symptoms – A single UK Centre Case Studies
Clinical Medicine 2022, Vol 22 No 2 March 2022
https://www.rcpjournals.org/content/clinmedicine/early/2022/02/01/clinmed.2021-0522.full-text.pdf


Long-term complications of COVID-19
Amar D. Desai,* Michael Lavelle,* Brian C. Boursiquot and Elaine Y. Wan
21 DEC 2021https://doi.org/10.1152/ajpcell.00375.2021
American Journal of Physiology-Cell PhysiologyVol. 322, No. 1
https://journals.physiology.org/doi/full/10.1152/ajpcell.00375.2021



Weaning from Mechanical Ventilator
https://www.cancertherapyadvisor.com/home/decision-support-in-medicine/critical-care-medicine/difficulty-weaning-from-mechanical-ventilation-failure-to-wean-respiratory-failure-ventilator-dependence/

14 Dec 2020
E-dimer
https://journals.lww.com/md-journal/Fulltext/2020/07310/D_dimer_surge_and_coagulation_disorders_in.119.aspx

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439969/#:~:text=In%20conclusion%20higher%20admission%20D,among%20patients%20with%20COVID%2D19.

https://jintensivecare.biomedcentral.com/articles/10.1186/s40560-020-00466-z


15  May update



May 14, 2020

NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19
Study enrolling adults with mild to moderate COVID-19 in the United States.
https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-hydroxychloroquine-azithromycin-treat-covid-19

14.05.2020
WHO to study Madagascar's drug to treat COVID-19
The World Health Organization (WHO) on Thursday said that it is in touch with Madagascar over its herbal drink Covid Organics (CVO) -- believed to cure coronavirus or COVID-19 patients.
https://www.aa.com.tr/en/africa/who-to-study-madagascars-drug-to-treat-covid-19-/1840971

13 May 2020

By mid-April, the Food and Drug Administration website had listed 72 active Covid drug trials. So far, only one drug, remdesivir, has shown promise in a major, randomized control trial to lessen the recovery time of Covid patients.

On April 17,  co-authors from institutions around the world published a paper detailing test of 12,000 drugs and identified 30 that appear to stop the virus from destroying human cells  on the preprint server bioRxiv.org. (The paper is currently being peer-reviewed for publication in a journal.) Out of the 30,  four have already been clinically tested for other uses. This helps others to plan clinical trials.
https://www.nytimes.com/2020/05/13/magazine/can-team-science-yield-a-covid-19-treatment.html




12 May 2020
COVID-19: 3-drug combo treatment may be successful
A phase II clinical trial has found that a combination of three drugs — interferon beta-1b, lopinavir-ritonavir, and ribavirin — plus standard care is successful in treating mild-to-moderate cases of COVID-19.

The results of a phase II trial suggest that a combination of three drugs may safely treat COVID-19.
This three-drug combination also shortens the duration of viral shedding — that is, the period during which the virus is detectable in a person’s body and transmissible to others. (Published in Lancet May 2020)
https://www.medicalnewstoday.com/articles/covid-19-3-drug-combo-treatment-may-be-successful

12 May
The World Health Organization said  that some treatments appear to be limiting the severity or length of the COVID-19 disease. It is a positive development.
In April,  WHO  said that there were 83 coronavirus vaccines in development globally, with six candidates -- half of them in China -- already in human trials.
https://www.livemint.com/news/world/who-says-some-treatments-appear-to-be-limiting-severity-of-coronavirus-11589282059930.html


9 May 2020

Anti-malaria drug hydroxychloroquine fails another test as a Covid-19 treatment.

Hydroxychloroquine is the only drug approved for treating hospitalised Covid-19 patients in India, where it is given in combination with the antibiotic azithromycin.

An observational study published in the New England Journal of Medicine (NEJM) concluded that the use of hydroxycholoquine neither lessened the need for patients requiring breathing assistance nor the risk of death.  1,376 consecutive patients in the emergency room with Covid-19 symptoms in the New York-Presbyterian Hospital and Columbia University Irving Medical Center in New York City were given the medicine.


Randomised-control trial evidence in larger numbers is needed and there is one , such multi-country solidarity trial being conducted by World Health Organization.  India is also participating in the solidarity trial.

Hydroxychloroquine is the only drug approved for treating hospitalised Covid-19 patients in India, where it is given in combination with the antibiotic azithromycin. It is also being given to health care workers and people at risk of exposure as a prophylaxis for Covid-19,

A small study in Brazil  was suspended after researchers found that high doses are required to fight Covid and the high does led to irregular heartbeats (heart arrhythmia).
https://www.hindustantimes.com/india-news/anti-malaria-drug-fails-another-test-as-a-covid-19-treatment-says-study/story-IadOtW6iRHIf7LMCA6AvSN.html


updated 4.4.2022, 13.12.2020.

Sunday, April 3, 2022

Thyroid Problems and Diseases




http://www.drug2day.com/index.php/drug/display/21558


India Medicine Prices


Brand
Company

ELTROXIN
GSK

PROLOID
(PARKE DAVIS) PFIZER




ROXIN
ZYDUS CADILA



THYROCHEK
MANKIND


THYRONORM
KNOLL (ABBOTT)


THYROUP
LUPIN

THYROWIN
PIRAMAL H.C

THYROX
MACLEODS

Adv Ther. 2019; 36(Suppl 2): 30–46.
Published online 2019 Sep 4. doi: 10.1007/s12325-019-01078-2
PMCID: PMC6822824
PMID: 31485977
Levothyroxine Dose Adjustment to Optimise Therapy Throughout a Patient’s Lifetime
Leonidas H. Duntascorresponding author1 and Jacqueline Jonklaas2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822824/

Effects of Altering Levothyroxine Dose on Energy Expenditure and Body Composition in Subjects Treated With LT4 
Mary H Samuels, Irina Kolobova, Meike Niederhausen, Jonathan Q Purnell, Kathryn G Schuff
The Journal of Clinical Endocrinology & Metabolism, Volume 103, Issue 11, November 2018, Pages 4163–4175, https://doi.org/10.1210/jc.2018-01203

No effect was found in the study.
https://academic.oup.com/jcem/article/103/11/4163/5078436


Does Hypothyroidism Affect Gastrointestinal Motility?
Hindawi
January 2009, Gastroenterology Research and Practice 2009(1687-6121):529802
DOI:10.1155/2009/529802
https://www.researchgate.net/publication/41910901_Does_Hypothyroidism_Affect_Gastrointestinal_Motility


ud. 4.4.2022, 30.3.2022
Pub 24.1.2016