Hypothyroidism and Increased Creatinine Levels and Renal Problems

January 11, 1999

Consistent Reversible Elevations of Serum Creatinine Levels in Severe Hypothyroidism

Stuart H. Kreisman, MDCM; James V. Hennessey, MD
http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/520024

Thyroid dysfunction and kidney disease

P Iglesias and J J Díez
Received 9 December 2008
Accepted 15 December 2008
2009 European Society of Endocrinology
http://www.eje-online.org/content/160/4/503.full

The Renal Manifestations of Thyroid Disease

Laura H. Mariani and Jeffrey S. Berns
Published online before print October 21, 2011, doi: 10.1681/ASN.2010070766
JASN January 1, 2012 vol. 23 no. 1 22-26
http://jasn.asnjournals.org/content/23/1/22.full

Increase in Creatinine Due to Use of Fenofibrate

Hypothyroid patients have increased cholesterol and tryglycerides. To manage this lipids problem, both statins and fenofibrates are used.

Nephrologie. 1999;20(1):41-4.

Fenofibrate increases blood creatinine, but does not change the glomerular filtration rate in patients with mild renal insufficiency

https://www.ncbi.nlm.nih.gov/pubmed/10081035

Nephron. 2002;92(3):536-41.

Fenofibrate increases creatininemia by increasing metabolic production of creatinine.

Hottelart C1, El Esper N, Rose F, Achard JM, Fournier A.
https://www.ncbi.nlm.nih.gov/pubmed/12372935

False Estimates of Elevated Creatinine

Manpreet Samra, MD and Antoine C Abcar, MD
The Permanent Journal, Perm J. 2012 Spring; 16(2): 51–52.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383162/

The fenofibrate can give an increased creatinine reading. It is reversible.