Wednesday, June 12, 2024

Endothelial Health - Impairment to Endothelial Function

 


Endothelial Health

The Importance of Endothelial Health!

The 1998 Nobel Prize in Medicine was awarded to three American researchers who discovered how endothelium produces a gas that actually regulates your entire cardiovascular system.  The  gas is Nitric Oxide – the master signaling molecule of your entire cardiovascular system.  


This health information webinar will teach you how to effectively nourish your endothelium for proper nitric oxide production, which has the potential to significantly improve cardiovascular health. 

https://www.youtube.com/watch?v=2MQCDQgojLg                       

Watch the above YouTube video to learn how and why!


https://no-more-heart-disease.com/endothelial-health/



Endothelial Function and Cardiovascular Disease


Cardiology University of Washington



8 Oct 2021  University of Washington Cardiovascular Grand Rounds 2021-2022

Francis Kim, MD

Learning Objectives:

-State why endothelial function is important for cardiologists

-Describe how endothelial function is measured

-Describe mechanisms of endothelial dysfunction


https://www.youtube.com/watch?v=s6Geqf9YWe0



Nitric Oxide - Enabler of Cardio Vascular Health

https://oldageindia.blogspot.com/2016/11/nitric-oxide-enable-of-cardio-vascular.html



The American Journal of Clinical Nutrition

Volume 93, Issue 3, March 2011, Pages 500-505

The American Journal of Clinical Nutrition

Endothelial function is impaired after a high-salt meal in healthy subjects1,2,3

Author links open overlay panelDickinson Kacie M, Clifton Peter M, Keogh Jennifer B

https://www.sciencedirect.com/science/article/pii/S0002916523022219



Dietary Sodium Restriction Reverses Vascular Endothelial Dysfunction in Middle-Aged/Older Adults With Moderately Elevated Systolic Blood Pressure

FREE ACCESS

Hypertension


Kristen L. Jablonski, Matthew L. Racine, Candace J. Geolfos, Phillip E. Gates, Michel Chonchol, Matthew B. McQueen, and Douglas R. Seals

J Am Coll Cardiol. 2013 Jan, 61 (3) 335–343


Clinical significance

The concept that high sodium intake has adverse CV effects independent of BP has been advanced previously (9,12). High dietary sodium impairs EDD even in rodents that are salt-resistant and, thus, do not exhibit increases in BP in response to a high-salt diet (13,18,20). Acute impairment of EDD in normotensive adults after sodium loading also is BP independent (11), and adults with elevated SBP who report lower sodium intake have enhanced EDD independent of BP (16). The present results extend these findings to sodium restriction and lend support to the overall hypothesis that sodium intake not only elevates BP but also exerts other adverse influences (12). The effects of sodium restriction on endothelial function reported here also complement previous findings that reducing sodium intake can rapidly de-stiffen large elastic arteries (21), another independent vascular risk factor for CVD (40). The improvements in these 2 common forms of arterial dysfunction, both predictors of CV events (3,4,40), suggest that DSR has strong potential for reducing CVD risk via broad vasculoprotective effects.

https://www.jacc.org/doi/10.1016/j.jacc.2012.09.010








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