Diagnosis and Management of Chronic Kidney Disease
Chronic kidney disease (CKD), is defined by a reduction in the estimated glomerular filtration rate (GFR). It is increasing because of the greater prevalence of obesity and hypertension but in greater part because of improved longevity. Because GFR declines 1% per year for every year of life after the third decade, living longer means that it is possible to outlive one’s renal function and to require renal replacement therapy to stay alive. Longevity increases the risk of developing diseases, such as diabetes, hypertension, and atherosclerotic vascular disease, that have direct adverse effects on kidney function.