The sufficient total daily dose of gabapentin started at 900 mg at study day 3. The cumulative proportions of patients reporting sufficient analgesia from gabapentin administration in both groups was over 5, 40, 80 and 90% at a total daily dose of 900, 1,200, 1,500, and 1,800 mg, respectively. This means that there was no need to increase the dose of gabapentin over 1,800 mg in more than 90% patients with neuropathic pain. However, there were 3.4% in the TID group and 2.2% in the QID group were non-responders were administrated gabapentin up to 3600 mg, and they also have received neural blockades and spinal cord stimulation after the study.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3726847/
