Saturday, April 29, 2023

Fatty Liver Disease

 


Interesting article

The Influence of Dietary Fat on Liver Fat Accumulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245577/



Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease


The potential sources of fats contributing to fatty liver  include peripheral fats stored in adipose tissue that flow to the liver by way of the plasma NEFA pool (pathway 1); fatty acids newly made within the liver through de novo lipogenesis (DNL) (pathway 2); and dietary fatty acids, which can enter the liver by two means: through spillover into the plasma NEFA pool  (pathway 3) and through the uptake of intestinally derived chylomicron remnants  (pathway 4).


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087172/

How Fat moves from intestine to adipose tissues

Mechanisms of chylomicron uptake into lacteals
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132563/


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