Gabapentin for Neuropathic Pain

 

The sufficient total daily dose of gabapentin started at 900 mg at study day 3. The cumulative proportions of patients reporting sufficient analgesia from gabapentin administration in both groups was over 5, 40, 80 and 90% at a total daily dose of 900, 1,200, 1,500, and 1,800 mg, respectively. This means that there was no need to increase the dose of gabapentin over 1,800 mg in more than 90% patients with neuropathic pain. However, there were 3.4% in the TID group and 2.2% in the QID group were non-responders were administrated gabapentin up to 3600 mg, and they also have received neural blockades and spinal cord stimulation after the study.

https://pmc.ncbi.nlm.nih.gov/articles/PMC3726847/

Champion Physiotherapy - Coimbatore, Tamil Nadu, India.

 

https://championphysio.in/

49/72-5, Cowley Brown Road,

R S Puram,

Coimbatore-641002.

Tamil Nadu, India.

Precautions for Degenerative Spondylolisthesis Patients

 Here are some precautions that patients with degenerative spondylolisthesis can take:

Avoid certain activities

Avoid activities that put too much strain on your lower back, like heavy weight lifting, full sit-ups, or high impact activities like jumping rope. You should also avoid excessive bending, twisting, or stooping. 

Take medication

Over-the-counter NSAIDs or acetaminophen can help with pain and inflammation. You can also take prescription anti-inflammatory medications called corticosteroids. However, you should not take over-the-counter pain relievers for more than 10 days in a row without talking to your doctor. 

Wear a brace

If you have a vertebra fracture, your doctor might recommend a back brace to stabilize your spine. 

Follow a rehabilitation program

Your doctor will outline a rehabilitation program to help you return to your activities. This might include exercises to strengthen your core and back muscles. 

Limit physical activity after surgery

After surgery, you should limit physical activity to gentle, low-impact movements for 8 to 10 weeks. 

(Google AI summary)

Good article

Eur Spine J. 2007 Nov 17;17(3):327–335. doi: 10.1007/s00586-007-0543-3

Diagnosis and conservative management of degenerative lumbar spondylolisthesis

Leonid Kalichman 1,✉, David J Hunter 1

https://pmc.ncbi.nlm.nih.gov/articles/PMC2270383/

You Can Change Overweight to Normal Weight - Become Healthy - Experience Sharing - Theory, Science and Practices

Overweight is a risk factor for health problems like high blood pressure, diabetes, triglycerides and cholesterol, blocks in arteries, joint pain etc.

If you are already suffering from these problems and doctors advise for lifestyle modification, the issue is more important to you.

Do you want to change to improve your health. If you want you can change. This article is being developed to be of help in reducing the weight. It is based on personal experience as well as the science described in published papers and practices based on science recommended by various doctors and exercise specialists.

The overweight problem is a serious global level problem. 2 billion persons are overweight and good number of of them are suffering from one health problem or other. Better understanding of the reasons for overweight development and for reducing it can help them to maintain better health.

Weight reduction consultancy advice. Thane - #weightReduction

There is plenty of information available online. I am also sharing lot of information. If you want personal discussion, encouragement, clarification and personal support, you can contact me. 

Narayana Rao  @knoltweet  https://twitter.com/knoltweet

https://www.facebook.com/kvssnrao

https://www.linkedin.com/in/narayana-rao-kvss-b608007/

How to Reduce Weight.

Understand how many calories you are spending per day.

Understand how many calories you are taking in through food per day.

You have to take less than what you are spending in a day to reduce weight.

To create the gap, you can do exercises and increase spending. You can reduce food intake. Normally both routes are attempted. The solution is so simple.  But in practice challenges arise. Only a small percentage of people are succeeding. 20% of the very serious effort making people are succeeding. You can be one of them. We can increase that percentage.  Understand more and practice without giving up.

Reduction of weight from 81 kg to 60 kg - An Ongoing Effort - Now at 63 kg - Read.

How many calories are you spending in a day?  Install Google Fit on your mobile and find out.

How many calories are you taking in food? Write a food diary and calculate calories in it.

What is normal calorie recommendation - 2000 per day for males, 1500 per day for females.

Please feel free to initiate discussion. Let us find answers through various sources.

What is overweight? What is obesity?

Overweight and Obesity are defined by a measure BMI.

BMI is weight in kg divided by square of height in meters.

Calculate your BMI using the website below.

https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmi-m.htm

BMI above 25 is overweight. BMI above 30 is obesity.

For Asians BMI above 23 is itself overweight.

Exercises for Weight Reduction

Walk for 30 minutes a day

Walk for 40 minutes a day.

Walk 5000 steps a day,

Walk 10000 steps a day

Cycling

Swimming

Targets for Weight Reduction

Create a gap of 500 calories per day. You can reduce 0.5 kg per week. 

Research on Weight Reduction - Health Problems Due to Overweight

2023

October 17, 2023

Research in Context: Obesity and metabolic health

The complexities of metabolism and body weight

Losing weight and reversing obesity might seem straightforward: eat fewer calories than you burn. But that’s not as easy as it sounds. This special Research in Context feature explores the many factors that affect the body’s metabolism and weight, some of which are difficult to control.

Losing weight and reversing obesity might seem straightforward: eat fewer calories than you burn. But many of us know that’s not as easy as it sounds.

“I think that most people overestimate how much conscious control we have, over long periods of time, over both the amount of food that we eat as well as the type of food that we eat,” says NIH metabolism researcher Dr. Kevin Hall.

https://www.nih.gov/news-events/nih-research-matters/research-context-obesity-metabolic-health

Uncovering Barriers and Facilitators of Weight Loss and Weight Loss Maintenance: Insights from Qualitative Research

Interesting information

Audrey Tay, Hannah Hoeksema, and Rinki Murphy

Spyridon N. Karras, Academic Editor

Nutrients. 2023 Mar; 15(5): 1297.

doi: 10.3390/nu15051297, PMCID: PMC10005538, PMID: 36904294

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10005538/

Weight Loss Stories

3.11.2024

Vidya Balan opens up on her weight loss.

https://epaper.lokmat.com/articlepage.php?articleid=LOKTIME_NPLT_20241030_9_2  

https://x.com/LokmatTimes_ngp/status/1851505653426069718

Ud. 2.1.2024

Pub. 1.1.2024

Is Lumbar Traction Contraindicated for Anterolisthesis?

https://now.aapmr.org/lumbar-spondylolisthesis/ 

Is lumbar traction contraindicated for spondylolisthesis?

Lumbar Traction:

Lumbar traction is a type of non-invasive therapy that applies a stretching force to the lumbar section of the spine, also known as the lower back just above the hips. This is done through pulleys and weight that help stretch the body and align the spine.

Yes, lumbar traction is contraindicated for spondylolisthesis. This means that physicians advise against the use of lumbar traction for patients that..

https://homework.study.com/explanation/is-lumbar-traction-contraindicated-for-spondylolisthesis.html

https://www.medindia.net/health/conditions/traction-for-lumbar-pain-contraindications.htm

Vertebral Disc Problems - Bulge, Herniation, Extrusion - Slip Disc - Sciatica

 

The probability of spontaneous regression of lumbar herniated disc: a systematic review

Review Clin Rehabil

. 2015 Feb;29(2):184-95. doi: 10.1177/0269215514540919. 

Results: The rate of spontaneous regression was found to be 96% for disc sequestration, 70% for disc extrusion, 41% for disc protrusion, and 13% for disc bulging. The rate of complete resolution of disc herniation was 43% for sequestrated discs and 15% for extruded discs.

Conclusions: Spontaneous regression of herniated disc tissue can occur, and can completely resolve after conservative treatment. Patients with disc extrusion and sequestration had a significantly higher possibility of having spontaneous regression than did those with bulging or protruding discs. Disc sequestration had a significantly higher rate of complete regression than did disc extrusion.

https://pubmed.ncbi.nlm.nih.gov/25009200/

Bush et al. studied 165 patients with sciatica thought to be due to lumbosacral nerve root compromise. They were treated with serial epidurals. Of the study cohort, 14% underwent surgical decompression and the rest made satisfactory clinical recovery. They were surprised to find on follow-up CT scanning that 64 of the 84 herniated/sequestered intervertebral discs showed partial or complete resolution at 1 year, whereas only 7 of the 27 bulging discs showed any resolution at 1 year. This was statistically significant.

Bush K, Cowan N, Katz DE, Gishen P. The natural history of sciatica associated with disc pathology. A prospective study with clinical and independent radiologic follow-up. Spine 1992; 17: 1205–12.

Research Article

Published Online March 2010

Share on

Conservatively treated massive prolapsed discs: a 7-year follow-up

Authors: RT Benson, SP Tavares, SC Robertson, R Sharp, and RW Marshall

ublication: The Annals of The Royal College of Surgeons of England

Volume 92, Number 2

Published Online March 2010

Conclusions

We can answer the questions that were posed at the outset of our study:

1.

It is safe to adopt a ‘wait-and-watch’ policy for cases of massive disc herniation if there is any early sign of clinical improvement.

2.

Where clinical progress is evident, 83% of cases of massive disc herniation will have sustained improvement.

3.

Only 17% of cases will have recurring crises of back pain and sciatica.

4.

If there is evidence of clinical improvement, massive disc prolapses do not appear to carry a risk of major nerve damage or cauda equina syndrome.

5.

Massive disc herniations usually reduce in volume and by 6 months most are only a third of their original size.

https://publishing.rcseng.ac.uk/doi/10.1308/003588410X12518836438840

Bulge - Herniation L5-S1

Detailed article

https://discseel.com/herniated-disc-l5-s1/

Top 25 Diabilities Globally

According to Lancet's Global Burden of diseases, the following is the list of top 25 disabilities.



1. Low back pain
2. Major depression
3. Iron deficiency anaemia
4. Neck pain
5. Other hearing loss
6. Migraine
7. Diabetes
8. COPD (pulmonary disease)
9. Anxiety disorders
10. Other musculosceletal
11. Schizophrenia
12. Falls
13. Osteoarthritis
14. Refraction accommodation
15. Asthma
16. Dysthmia (mood disorder)

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30925-9/fulltext

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00757-8/fulltext

https://www.nejm.org/cms/10.1056/NEJMra1201534/asset/529ea5d9-cfdc-455d-ae27-ab02b7bd057b/assets/images/large/nejmra1201534_t2.jpg

Ud. 26.10.2024

Pub. 9.6.2015